Elizabeth Ann Duke married Isaac M. Clayton, brother of John Anderson Clayton, in west Georgia in the 1830s. They moved to Tallapoosa County, AL by 1850.
Sources
Coweta County, GA Administration and Guardian Bonds, Vol. A, pp 64-65
1835 Coweta County, Georgia, Joshua Thornton Duke, son of John and Polly Duke, "was this day appointed guardian of the person and property of Elizabeth Duke and Lucinda Duke orphan children of John Duke, deceased.
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DNA Connections
It may be possible to confirm family relationships with Elizabeth by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Elizabeth: