"Connecticut Births and Christenings, 1649-1906," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:F748-VBL : 11 February 2018), Isaac Osborn, 22 Jul 1744; citing ; FHL microfilm unknown.
"Connecticut Deaths and Burials, 1772-1934," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:F769-56B : 9 February 2018), Deacon Isaac Osborn, 25 Mar 1826; citing Litchfield, Connecticut, reference ; FHL microfilm 3,178.
Find A Grave, database and images (https://www.findagrave.com : accessed 20 February 2019), memorial page for Isaac Osborn (22 Jul 1744–25 Mar 1826), Find A Grave: Memorial #28804717, citing West Cemetery, Litchfield, Litchfield County, Connecticut, USA ; Maintained by Brian Gallagher (contributor 47661632). (no photo)
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DNA Connections
It may be possible to confirm family relationships with Isaac by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Isaac: