Francis was born about 1722. He passed away in 1803.
Sources
"England Marriages, 1538–1973 ," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NNG1-D5Z : 9 March 2018), Francis Smith and Sarah Bonham, 21 Oct 1751; citing Leckhampstead, Buckingham, England, reference Item 1, index based upon data collected by the Genealogical Society of Utah, Salt Lake City; FHL microfilm 1,999,418.
"England Deaths and Burials, 1538-1991," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:J8XH-BM5 : 9 March 2018), Francis Smith, burial 25 Apr 1803; citing Leckhampstead, Buckingham, England, index based upon data collected by the Genealogical Society of Utah, Salt Lake City; FHL microfilm 1,999,418.
"England Births and Christenings, 1538-1975," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:JQHX-ZYN : 9 March 2018, Francis Smyth in entry for John Smyth, ); citing Item 1, index based upon data collected by the Genealogical Society of Utah, Salt Lake City; FHL microfilm 1,999,418.
"England Marriages, 1538–1973 ," database, FamilySearch (https://familysearch.org/ark:/61903/1:1:NNG1-X2V : 9 March 2018), Francis Smyth and Sarah Whitehead, 02 Sep 1781; citing Leckhampstead, Buckingham, England, reference Item 1, index based upon data collected by the Genealogical Society of Utah, Salt Lake City; FHL microfilm 1,999,418.
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DNA Connections
It may be possible to confirm family relationships with Francis by comparing test results with other carriers of his Y-chromosome or his mother's mitochondrial DNA.
However, there are no known yDNA or mtDNA test-takers in his direct paternal or maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Francis: