Born, likely, at Hopetoun House, on 1 Mar 1736, she married, at Hopetoun, 24 July 1754, Henry Douglas, Earl of Drumlanrig, eldest son of Charles Douglas, third Duke of Queensberry.
He died, without issue, 19 October 1754, and she died, at Hopetoun, 7 April 1756, and was buried at Durisdeer, her husband's estates at Drumlanrig, beside her husband.
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