Not sure about her birth or death dates. We know that she married John Bradley in 1733, so born before then and died after then.
Sources
The Name and Family of Bradley, Melvin James Bradley
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DNA Connections
It may be possible to confirm family relationships with Margaret by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Margaret: