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She was the younger daughter of Sir Harbottle Grimston, 2nd Baronet Grimston of Bradfield Hall, Essex, Master of the Rolls, and Mary Croke, daughter of Sir George Croke, Justice of the Common Pleas.
In 1650 she married Sir George Grobham Howe, Baronet, MP.
She died in 1709, and was buried in Berwick, St. Leonard's, County of Wiltshire.
Her Will was dated 4 November 1707 and 10 January 1708, and was proved on 11 May 1709 (P.C.C. 118 Lane).
Baroness Howe, Collins's Peerage of England, Genealogical, Biographical and Historical, by Arthur Collins and Sir Egerton Brydges, Vol. VIII, London, 1812.
Pedigree of Howe, Visitation of England and Wales, Edited by Joseph Jackson Howard and Frederick Arthur Crisp, Volume 13, 1919.
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