No Source for Catherine's surname at birth, Kizer is only a possibility.
Husband's Wikitree biography. - says that Catherine's son called a Henry Kizer "uncle" - which means that Catherine could be a Kizer OR her sister could have married a Kizer OR her husband's sister could have married a Kizer. Giving Catherine "Kizer" as a last name without a source could keep one from recognizing the correct last name.
Another possibility is Barger. See FamilySearch entry for Catherine D Barger .
John Leppard, of East Gwillimbury, yeoman, died Intestate 28 September, 1803.
Bond dated 11 January, 1804 between Catherine Leppard, Widow, Henry Leppard, son of East Gwillimbury and John Bogart, yeoman of Whitchurch
Administrator of Estate: Catherine Leppard, widow
Inventory
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DNA Connections
It may be possible to confirm family relationships with Catherine by comparing test results with other carriers of her mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Catherine: