Morin, Gail. First Metis Families of Quebec, 1622-1748, Volume 2: Jean Nicolet and a Nipissing Woman. New Genealogy, pub. 2014. (E-book for E-Reader edition). Individual # 1022 - Jean Regis Lessard.
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DNA Connections
It may be possible to confirm family relationships with Jean Régis by comparing test results with other carriers of his ancestors' Y-chromosome or mitochondrial DNA.
Y-chromosome DNA test-takers in his direct paternal line on WikiTree: