Prudence was born in 1789. She is the daughter of Peter Main and Patience Eggleston. She married circ. 1807 Stephen Palmer.
Sources
Genealogical Record of Nathaniel Babcock, Simeon Main, Isaac Miner, Ezekiel Main compiled by Cyrus H. Brown, Westerly R.I. The Everett Press, Boston, 1909 pg.147
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DNA Connections
It may be possible to confirm family relationships with Prudence by comparing test results with other carriers of her ancestors' mitochondrial DNA.
However, there are no known mtDNA test-takers in her direct maternal line.
It is likely that these autosomal DNA test-takers will share some percentage of DNA with Prudence: